Clinical Research & Studies
Expert synthesis of clinical frameworks, condition protocols, and standard-of-care medical literature.
Graded exercise therapy and pacing for ME/CFS: a contested evidence base
The NICE guideline now centres ME/CFS care on managing the worsening that follows activity, and says graded exercise should not be offered.
Conservative care for sciatica: what the evidence shows across the options
Most sciatica improves over weeks to months. Non-surgical treatments show small, mostly short-term benefits, on weak evidence.
Acupuncture for preventing migraine: what the evidence shows
Acupuncture may reduce how often migraines happen, with fewer side effects than some preventive medicines. The benefit over placebo is small.
Manual therapy or exercise for shoulder impingement: what the evidence shows
For rotator cuff shoulder pain, exercise is the core treatment. Evidence that adding hands-on therapy helps further is mixed.
Why hearing aids end up in a drawer: what the evidence shows about use and adherence
Many factors can affect hearing aid use. Research on interventions to improve use shows small effects, with low-quality evidence.
Exercise during and after pregnancy: what the Canadian guideline and the evidence show
Prenatal exercise may reduce prenatal depressive symptoms; pelvic floor training may lower incontinence risk in women continent before pregnancy.
Return-to-sport criteria after ACL reconstruction: what the evidence shows
Cohort studies link delaying return to sport to at least 9 months after ACL reconstruction, and passing functional tests, with lower re-injury risk.
Foot orthoses for plantar fasciitis and plantar heel pain: what the evidence shows
Foot orthoses may ease plantar heel pain in the medium term. Trials found no clear function benefit and no long-term benefit over a a dummy insert.
Early mobilization versus rest and collars for whiplash: what the evidence shows
Guidelines favour staying active over rest and collars for whiplash. The overall quality of evidence for whiplash treatments has been limited.
Tinnitus retraining therapy versus sound therapy alone: what the evidence shows
A single low-quality trial favoured tinnitus retraining therapy, but a larger trial found no difference from counselling with placebo sound or standard care.
Dry needling for myofascial trigger point pain: what the evidence shows
Dry needling may help reduce pain and improve range of motion in the short term. Serious adverse events appear to be rare.
Rehabilitation for the arm and hand after stroke: what the evidence shows
After a stroke, task-based therapy and training that restricts the stronger arm both have reasonable support; wider evidence is thin.
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